Acetic Acid Chlorhexidine Ketoconazole
This is a topical combination medication containing an antifungal (ketoconazole), an antiseptic (chlorhexidine), and an acidifying agent (acetic acid). It is primarily used to treat fungal skin infections that may be complicated by bacterial co-infection, such as seborrheic dermatitis, dandruff, and certain ear conditions. The multi-ingredient formulation targets multiple types of pathogens simultaneously to improve treatment efficacy.
A topical antifungal-antiseptic combination used for treating fungal infections of the skin, often those complicated by bacterial co-infection.
Key facts at a glance
- RxNorm
- 1439947
- Generic
- Acetic Acid / Chlorhexidine / Ketoconazole
- Class
- multi-ingredient
- Brands
- Mal-A-Ket
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of seborrheic dermatitis, dandruff, pityriasis versicolor, and other superficial fungal skin infections. May also be used for certain ear conditions (otitis externa) when bacterial or fungal involvement is suspected.
Ketoconazole works by inhibiting fungal cell membrane synthesis. Chlorhexidine provides broad-spectrum antibacterial activity. Acetic acid helps create an acidic environment that inhibits pathogen growth and may enhance penetration of active ingredients.
For topical use only; avoid contact with eyes and mucous membranes. May cause skin irritation, dryness, or burning sensation in some users. Effectiveness may be reduced if used with certain soaps or cleansers. Consult a healthcare provider if symptoms do not improve after recommended treatment duration.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy