Acetic Acid Hydrocortisone
Acetic Acid/Hydrocortisone is a combination ear drop medication used to treat infections and inflammation of the external ear canal, commonly known as swimmer's ear. The acetic acid works by creating an acidic environment that prevents the growth of bacteria and fungi, while hydrocortisone reduces swelling, itching, and discomfort associated with the infection. This medication is typically prescribed when there is both an infectious and inflammatory component to the ear condition.
A combination ear drop medication that treats external ear infections by combining an antifungal/antibacterial agent with an anti-inflammatory steroid.
Key facts at a glance
- RxNorm
- 466530
- Generic
- Acetic Acid / Hydrocortisone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of otitis externa (swimmer's ear), including bacterial and fungal ear canal infections, as well as inflammatory conditions of the external ear canal such aseczematous otitis externa. May also be used for acute diffuse otitis externa and chronic inflammatory ear conditions.
Acetic acid creates an acidic environment in the ear canal (typically lowering pH to around 3-4), which inhibits the growth of bacteria and fungi. Hydrocortisone is a corticosteroid that works by reducing inflammation, decreasing vascular permeability, and suppressing the immune response, thereby relieving associated pain, itching, and swelling.
For otic use only; should not be used in the eyes. Patients with a perforated eardrum or tympanostomy tubes should use with caution and only under medical supervision. Avoid contamination of the dropper tip. Complete the full course of treatment as prescribed, even if symptoms improve. Common side effects may include temporary stinging or burning upon application.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy