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Acetic Acid Salicylic Acid

Published: July 27, 2026Updated: August 27, 2026

Acetic Acid/Salicylic Acid is a topical combination medication used to treat common skin conditions such as warts, corns, and calluses. Salicylic acid acts as a keratolytic agent, softening and breaking down keratin in thickened skin, while acetic acid provides antimicrobial properties and helps maintain an acidic environment unfavorable for certain skin lesions. This medication is available over-the-counter in various topical solution and pad formulations.

Quick summary

Topical combination medication for removing warts, corns, and calluses by softening thickened skin.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
690205
Generic
Acetic Acid / Salicylic Acid
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of common warts (verruca vulgaris), plantar warts, corns, and calluses. Primarily used for superficial, non-genital skin growths caused by human papillomavirus (HPV) or friction/pressure.

Salicylic acid is a keratolytic that softens and dissolves the protein (keratin) forming the wart or thickened skin, allowing gradual removal. Acetic acid (vinegar) provides acidic conditions with mild antimicrobial properties that complement the keratolytic action.

For external use only. Avoid contact with healthy skin, face, moles, birthmarks, or genital warts. Do not use on irritated, infected, or red skin, or by individuals with diabetes or poor circulation. May cause local skin irritation, burning, or peeling. Consult a healthcare provider if warts are painful, change appearance, or do not improve after 2 weeks.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy