Aflibercept-Yszy
Aflibercept-Yszy is an anti-VEGF (vascular endothelial growth factor) inhibitor medication designed to block abnormal blood vessel formation and reduce fluid leakage in the eye. It is administered as an intravitreal injection into the eye and is used primarily in ophthalmology for conditions involving retinal dysfunction.
Aflibercept-Yszy is an anti-VEGF injection medication used to treat certain eye conditions by inhibiting abnormal blood vessel growth and fluid leakage.
Key facts at a glance
- RxNorm
- 2715399
- Generic
- Aflibercept-Yszy
- Class
- pin-variant
- Brands
- Opuviz
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of neovascular (wet) age-related macular degeneration (AMD), diabetic macular edema (DME), macular edema following retinal vein occlusion (RVO), and diabetic retinopathy. Individual indications may vary by formulation and regional approval status.
Aflibercept-Yszy is a recombinant fusion protein that acts as a soluble decoy receptor, binding to VEGF-A, VEGF-B, and placental growth factor (PlGF). By binding these growth factors, it prevents them from interacting with their natural receptors, thereby inhibiting angiogenesis and reducing vascular permeability.
Administered via intravitreal injection by a qualified healthcare professional. Common side effects may include eye irritation, discomfort, floaters, or increased intraocular pressure. Rare but serious risks include endophthalmitis and retinal detachment. Patients should report any signs of infection or vision changes immediately. This is a biosimilar or variant formulation of aflibercept; specific details may differ from reference products.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy