Ajmalicine Almitrine
Ajmalicine/Almitrine is a combination medication containing two distinct active ingredients. Ajmalicine (raubasine) is an alpha-adrenergic antagonist traditionally used for cerebrovascular disorders, while almitrine acts as a respiratory stimulant on peripheral chemoreceptors. This combination has been used primarily for conditions involving cognitive impairment and cerebral circulation issues.
This multi-ingredient medication combines a cerebral blood flow enhancer with a respiratory stimulant for cognitive and cerebrovascular indications.
Key facts at a glance
- RxNorm
- 1009117
- Generic
- Ajmalicine / Almitrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for cerebrovascular insufficiency, age-related cognitive decline, and memory disorders. May also be employed in cases of chronic respiratory conditions where improved oxygenation is desired. The combination targets both cognitive function and cerebral circulation.
Ajmalicine acts as an alpha-adrenergic receptor antagonist, causing vasodilation in cerebral vessels and improving blood flow. Almitrine stimulates peripheral chemoreceptors, enhancing respiratory drive and improving oxygen uptake. Together they address both vascular and respiratory aspects of oxygen delivery to tissues.
Side effects may include gastrointestinal disturbances, dizziness, and headache. Should be used with caution in patients with hypotension, cardiac arrhythmias, or severe hepatic/renal impairment. Safety in pregnancy and lactation not well established. Medical supervision is required for appropriate dosing and duration of treatment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy