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Ajmaline Almitrine

Published: July 27, 2026Updated: August 27, 2026

This multi-ingredient medication combines ajmaline, a Class Ia antiarrhythmic agent derived from Rauwolfia serpentina, with almitrine, a respiratory stimulant. The combination is used for managing specific cardiac arrhythmias alongside respiratory conditions requiring improved oxygenation.

Quick summary

A combination medication pairing an antiarrhythmic agent with a respiratory stimulant for cardiac and pulmonary indications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1009054
Generic
Ajmaline / Almitrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Ajmaline component is used for treating supraventricular and ventricular arrhythmias, including diagnostic testing for Brugada syndrome. Almitrine component addresses chronic respiratory conditions with hypoxemia, particularly COPD-related breathing difficulties.

Ajmaline blocks sodium channels in cardiac tissue, prolonging action potential duration and stabilizing cardiac membranes. Almitrine enhances pulmonary ventilation by stimulating peripheral chemoreceptors, improving alveolar oxygen uptake and reducing hypoxemia.

Requires cardiac monitoring during administration due to proarrhythmic risk. Contraindicated in patients with severe conduction abnormalities, uncompensated heart failure, or known hypersensitivity. Should be used with caution in hepatic impairment as both agents undergo hepatic metabolism. May interact with other QT-prolonging medications.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy