Aliskiren Amlodipine
Aliskiren/Amlodipine is a combination medication used to treat high blood pressure (hypertension). It combines a direct renin inhibitor with a calcium channel blocker to help lower blood pressure through complementary mechanisms. This combination is typically prescribed when single-agent therapy is insufficient for adequate blood pressure control.
A combination blood pressure medication pairing a renin inhibitor with a calcium channel blocker for enhanced antihypertensive effect.
Key facts at a glance
- RxNorm
- 1009219
- Generic
- Aliskiren / Amlodipine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of essential hypertension (high blood pressure) in patients who require combination therapy to achieve adequate blood pressure control.
Aliskiren inhibits renin, an enzyme that starts the process leading to elevated blood pressure, while amlodipine blocks calcium from entering blood vessel walls, causing them to relax and widen. Together, they lower blood pressure through two complementary pathways.
Not recommended during pregnancy due to potential harm to the fetus. May cause dizziness or swelling; avoid alcohol and excessive sun exposure. Patients with diabetes, kidney impairment, or volume depletion should use with caution, particularly with ACE inhibitors or ARBs.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy