Aliskiren Valsartan
Aliskiren/valsartan is a combination medication used to treat high blood pressure (hypertension) in adults. It combines two blood pressure-lowering agents that work at different points in the renin-angiotensin system to more effectively reduce blood pressure than either component alone. This medication is typically prescribed when single-agent therapy is insufficient for adequate blood pressure control.
A combination blood pressure medication pairing a direct renin inhibitor with an angiotensin receptor blocker for enhanced hypertension control.
Key facts at a glance
- RxNorm
- 900937
- Generic
- Aliskiren / Valsartan
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of essential hypertension (high blood pressure) in adults when monotherapy is inadequate. May be used as initial therapy in patients requiring multiple agents to achieve blood pressure targets.
Contains two complementary agents: aliskiren (direct renin inhibitor) blocks renin's conversion of angiotensinogen to angiotensin I, while valsartan (angiotensin II receptor blocker) prevents angiotensin II from binding to its receptors. Together, they provide dual blockade of the renin-angiotensin-aldosterone system (RAAS) at different points.
Contraindicated in pregnancy (risk of fetal harm), diabetes patients using ARBs or ACE inhibitors, and patients with angioedema history. May cause hyperkalemia, hypotension, and kidney impairment. Avoid concomitant ACE inhibitor or ARB use. Not recommended for patients with diabetes or renal impairment (eGFR <60).
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy