Allopurinol / Benbromarone
This combination medication is used to treat hyperuricemia (elevated uric acid levels) and gout. It combines two different approaches to lowering uric acid: one ingredient reduces uric acid production while the other increases its excretion through the kidneys. This dual mechanism makes it useful for patients who don't respond adequately to single-agent therapy.
A combination medication that lowers uric acid through two complementary mechanisms for the treatment of gout and hyperuricemia.
Key facts at a glance
- RxNorm
- 813631
- Generic
- Allopurinol / Benzbromarone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is primarily used to treat chronic gout and hyperuricemia, particularly in patients who have not achieved adequate control with single-agent urate-lowering therapy. It may be prescribed when there is a need for more aggressive uric acid reduction or in cases of tophaceous gout.
The combination works through two complementary mechanisms: Allopurinol inhibits xanthine oxidase, an enzyme involved in the production of uric acid, thereby reducing its synthesis. Benzbromarone acts as a uricosuric agent, increasing uric acid excretion through the kidneys by inhibiting its reabsorption in the renal tubules. Together, these actions provide a dual approach to lowering serum uric acid levels.
Patients should maintain adequate hydration to reduce the risk of kidney stones. Liver function tests may be monitored during treatment, particularly with benzbromarone. This medication is typically initiated after an acute gout attack has resolved. Patients should be aware of potential drug interactions and should inform healthcare providers of all medications being taken.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy