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Allopurinol Sodium

Published: July 26, 2026Updated: August 25, 2026

Allopurinol Sodium is a xanthine oxidase inhibitor used to reduce uric acid production in the body. It is primarily prescribed for patients with gout, hyperuricemia, and certain cancer patients undergoing chemotherapy to prevent tumor lysis syndrome-related uric acid buildup. This medication requires consistent use and may initially trigger gout flares before providing symptom relief.

Quick summary

Allopurinol Sodium lowers uric acid levels to prevent gout attacks and related complications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
80566
Generic
Allopurinol Sodium
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Chronic gout with recurrent attacks, tophi (uric acid deposits), gouty arthritis, hyperuricemia associated with chemotherapy (tumor lysis syndrome prevention), and recurrent calcium nephrolithiasis (kidney stones) associated with hyperuricemia.

Allopurinol inhibits xanthine oxidase, an enzyme responsible for converting hypoxanthine and xanthine to uric acid. By blocking this pathway, it reduces uric acid production and lowers serum and urinary uric acid levels.

May precipitate acute gout attacks during initial therapy; concurrent colchicine or NSAIDs are often prescribed. Requires adequate hydration to prevent kidney stone formation. Can cause serious skin reactions (Stevens-Johnson syndrome) and requires regular monitoring of liver function and blood counts. Should be taken with food to reduce GI upset.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy