Alprazolam / Sulpiride
Alprazolam/Sulpirida is a combination medication pairing a benzodiazepine anxiolytic with an atypical antipsychotic. This combination may be prescribed for anxiety disorders or mood conditions requiring both rapid-acting anxiolytic effects and antipsychotic/neuroleptic properties. The specific use depends on the condition being treated and the formulation ratios.
A combination medication containing an anxiolytic and antipsychotic for treating anxiety and related psychiatric conditions.
Key facts at a glance
- RxNorm
- 817112
- Generic
- Alprazolam / Sulpiride
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
May be used for anxiety disorders, mixed anxiety-depressive states, and conditions where both anxiolytic and antipsychotic/neuroleptic effects are desired. Specific indications vary by formulation and prescribing physician's judgment.
Alprazolam produces anxiolytic and sedative effects through GABA-A receptor enhancement, while Sulpirida acts primarily as a dopamine D2/D3 receptor antagonist with partial agonist activity at serotonin 5-HT2A receptors. Together they may address both anxiety symptoms and underlying dopaminergic activity.
Benzodiazepine component carries risks of dependence, tolerance, and withdrawal. Antipsychotic component may cause extrapyramidal symptoms, prolactin elevation, and metabolic effects. Combined use requires careful monitoring for sedation, cognitive impairment, and drug interactions. Use only as prescribed; do not discontinue abruptly.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy