Alprenolol
Alprenolol Hydrochloride is a non-selective beta-blocker medication historically used to manage cardiovascular conditions such as hypertension, angina pectoris, and certain cardiac arrhythmias. It works by blocking both beta-1 and beta-2 adrenergic receptors, reducing heart rate and blood pressure. The medication also exhibits mild intrinsic sympathomimetic activity (partial agonist properties), which may reduce some adverse effects associated with complete beta-blockade.
A non-selective beta-blocker used to treat hypertension, angina, and arrhythmias by reducing heart rate and blood pressure.
Key facts at a glance
- RxNorm
- 81947
- Generic
- Alprenolol Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for hypertension (high blood pressure), angina pectoris (chest pain), and certain cardiac arrhythmias. May also have been used for migraine prevention and anxiety management in some cases.
Blocks both beta-1 receptors in the heart (reducing heart rate and contractility) and beta-2 receptors in blood vessels and bronchi. Has intrinsic sympathomimetic activity (ISA), meaning it produces mild partial agonism at beta receptors while primarily acting as an antagonist.
Should not be discontinued abruptly as this may precipitate rebound cardiac events. Contraindicated in patients with severe bradycardia, heart block, decompensated heart failure, and asthma (due to non-selective beta-2 blockade). May mask symptoms of hypoglycemia and should be used cautiously in diabetic patients.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy