Alverine
Alverine is an antispasmodic drug used to manage functional gastrointestinal disorders like IBS by relaxing the smooth muscle in the gut.
Alverine is an antispasmodic used to relieve intestinal cramping and IBS-related abdominal pain by relaxing gut smooth muscle.
Key facts at a glance
- ATC
- A03AX08
- RxNorm
- 17627
- Generic
- Alverine
- Class
- atc-a03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse with caution
avoid use while breastfeeding unless benefits outweigh risks
monitor infant for adverse effects
Use with caution and monitor for adverse effects.
geriatric
elderlyno adjustment needed
use standard adult dosage with monitoring
monitor for side effects and comorbidities
pediatric_age
children under 12not recommended
do not use in children under 12 years of age
not applicable
Use of this medication in this population requires careful consideration of risks and benefits.
pediatric_age
adolescents 12 18use with caution
use only if benefits outweigh risks
monitor for adverse effects
Use with caution and monitor for adverse effects.
renal_impairment
mildno adjustment needed
use standard dosage
routine monitoring
renal_impairment
severedose reduction may be required
use with caution and consider dose reduction
monitor renal function closely
Use with caution and monitor for adverse effects.
hepatic_impairment
mildno adjustment needed
use standard dosage
routine monitoring
hepatic_impairment
severedose reduction may be required
use with caution and consider dose reduction
monitor liver function closely
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information for antispasmodic agents
Drug class
Drug class information
Common uses
Common therapeutic uses
Mechanism of action
Pharmacological mechanism
Alverine is primarily used to treat irritable bowel syndrome (IBS) and related functional gastrointestinal disorders characterized by abdominal pain, cramping, bloating, and intestinal spasms. It may also be used for conditions involving smooth muscle spasms in the digestive tract.
Alverine is a smooth muscle relaxant that acts directly on intestinal smooth muscle. It helps reduce intestinal contractions and relieves spasms by modulating calcium channels in smooth muscle cells, thereby decreasing pain and discomfort associated with gut hyperactivity.
Alverine is generally well-tolerated but may cause mild side effects such as headache, nausea, or dizziness in some individuals. It should not be used by patients with certain conditions including paralytic ileus or if allergic to the medication. Patients should consult their healthcare provider before use, especially if pregnant, breastfeeding, or taking other medications.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy