Alverine / Simethicone
Alverine/Simethicone is a combination medication used to treat symptoms of irritable bowel syndrome (IBS) and related functional gastrointestinal disorders. Alverine acts as a smooth muscle relaxant to reduce intestinal cramping and spasms, while Simethicone helps relieve bloating and discomfort by breaking down gas bubbles in the digestive tract. This medication is typically prescribed for adults experiencing abdominal pain, bloating, and altered bowel habits associated with IBS.
A combination antispasmodic and antiflatulent medication used to relieve abdominal cramps, bloating, and gas related to IBS and digestive disorders.
Key facts at a glance
- RxNorm
- 1007232
- Generic
- Alverine / Simethicone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for irritable bowel syndrome (IBS), including symptom relief of abdominal pain, cramping, bloating, and excessive gas. May also be prescribed for other functional gastrointestinal disorders characterized by intestinal spasms and gas-related discomfort.
Alverine is an antispasmodic agent that works by directly relaxing smooth muscle in the walls of the intestines and other organs, reducing painful contractions and cramping. Simethicone is an antiflatulent that reduces the surface tension of gas bubbles in the digestive tract, allowing them to combine and be more easily expelled or absorbed.
Not recommended for acute abdominal pain of unknown origin, intestinal obstruction, or paralytic ileus. Should not be used by individuals with known hypersensitivity to either component. Patients with glaucoma or urinary retention should use with caution due to potential anticholinergic effects. Not typically recommended during pregnancy or breastfeeding unless specifically prescribed by a healthcare provider. Always follow prescribing information and consult your healthcare provider for personalized medical advice.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy