Ambroxol / Clobutinol
Ambroxol/Clobutinol is a combination medication used to treat respiratory conditions characterized by excessive or thick mucus and associated coughing. Ambroxol acts as a mucolytic agent to help loosen and clear respiratory secretions, while Clobutinol provides cough-suppressing effects. This combination is typically prescribed for acute and chronic bronchopulmonary disorders such as bronchitis, asthma, and COPD when both mucus clearance and cough relief are needed.
A combination cough and cold medication pairing a mucolytic (Ambroxol) with a cough suppressant (Clobutinol) for respiratory conditions with problematic mucus and coughing.
Key facts at a glance
- RxNorm
- 821034
- Generic
- Ambroxol / Clobutinol
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acute and chronic bronchopulmonary diseases associated with thick, viscous mucus and productive cough, including bronchitis, asthma, COPD exacerbations, and other respiratory tract infections where both mucus clearance and cough suppression are clinically beneficial.
Ambroxol stimulates surfactant production and breaks down mucopolysaccharide fibers in mucus, reducing its viscosity and facilitating clearance. Clobutinol acts on the cough center in the brainstem to suppress the cough reflex, providing symptomatic relief from persistent coughing.
Not recommended during pregnancy, particularly the first trimester, or while breastfeeding. May cause mild gastrointestinal discomfort or transient taste disturbances. Clobutinol-containing products have been withdrawn from some markets due to cardiac safety concerns; availability varies by country. Patients with a history of cardiac conditions should use with caution and only under medical supervision.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy