Amcinonide
Amcinonide is a topical corticosteroid medication used to treat inflammatory and itchy skin conditions such as eczema, dermatitis, and psoriasis. It is typically prescribed when milder corticosteroids have not been effective enough.
Amcinonide is a potent topical steroid that reduces inflammation and itching of the skin.
Key facts at a glance
- ATC
- D07AC11
- RxNorm
- 17652
- Generic
- Amcinonide
- Class
- atc-d07
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- cream, ointment
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
9 groupspregnancy
first trimesteruse lowest effective dose for shortest duration
avoid use on large surface areas or under occlusive dressings during pregnancy unless benefits outweigh risks
regular prenatal checkups
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse lowest effective dose for shortest duration
avoid application to large body surface areas
routine prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesterminimize use and duration
avoid extensive use particularly near term
fetal monitoring in late pregnancy
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse minimal amount and short duration
do not apply to breasts or nipple area; if needed on other areas, wash thoroughly before breastfeeding
monitor infant for signs of adrenal suppression if extensive use
Use with caution and monitor for adverse effects.
pediatric_age
infantsuse with extreme caution, reduced potency and duration
not recommended for infants due to higher skin permeability and risk of systemic absorption; avoid on diaper area under occlusive dressings
monitor for signs of HPA axis suppression
Use with caution and monitor for adverse effects.
pediatric_age
childrenuse lower potency preparations when possible and limit treatment duration
avoid use on large areas, prolonged use, or under occlusive dressings in children
monitor growth and development with long-term use
Use with caution and monitor for adverse effects.
geriatric
elderlyuse with caution, start with lower frequency
skin may be thinner in elderly; avoid prolonged use on large areas; monitor for skin atrophy
periodic skin examination for atrophy or telangiectasia
Use with caution and monitor for adverse effects.
renal_impairment
mild to moderateno adjustment typically required
standard topical use considered safe due to minimal systemic absorption
no specific monitoring needed
hepatic_impairment
mild to moderateno adjustment typically required
standard topical use considered safe due to minimal systemic absorption
no specific monitoring needed
Statistics and clinical data
First approved
Initial FDA approval year for topical formulation
Drug class
Pharmacological classification based on ATC system
Potency classification
Relative potency ranking among topical corticosteroids
Common indications
FDA-approved therapeutic uses
Treats various inflammatory and pruritic dermatological conditions including atopic dermatitis, contact dermatitis, eczema, psoriasis, and other corticosteroid-responsive skin disorders.
As a topical corticosteroid, amcinonide works by suppressing the immune response and reducing inflammation in the skin. It decreases the production of inflammatory mediators and inhibits the migration of inflammatory cells to the affected area.
Amcinonide is a potent topical steroid and should not be used on the face, groin, or underarms unless specifically directed by a healthcare provider. It should not be used on broken or infected skin, and treatment should be limited to short durations to minimize side effects such as skin thinning. Patients should avoid covering treated areas with occlusive dressings unless instructed. Use during pregnancy or breastfeeding should be discussed with a healthcare provider.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy