Amiloride / Furosemide
Amiloride/furosemide is a combination diuretic medication used to treat fluid retention (edema) and high blood pressure. It combines a loop diuretic (furosemide) with a potassium-sparing diuretic (amiloride) to enhance fluid removal while helping preserve potassium levels in the body. This combination may be prescribed when single-agent diuretic therapy is insufficient or when potassium supplementation needs to be avoided.
A combination diuretic used to reduce fluid retention while helping maintain potassium levels.
Key facts at a glance
- RxNorm
- 818351
- Generic
- Amiloride / Furosemide
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats fluid retention associated with heart failure, liver cirrhosis, and kidney disorders; also used for management of hypertension when potassium conservation is desired.
Furosemide blocks sodium reabsorption in the ascending loop of Henle (promoting water and sodium excretion), while amiloride works in the distal tubule to reduce potassium loss, helping maintain electrolyte balance.
Regular monitoring of kidney function and electrolytes (especially potassium) is essential. Patients should report signs of dehydration, muscle weakness, or irregular heartbeat. May interact with other medications affecting blood pressure or electrolytes.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy