Skip to content

Aminophylline / Ephedrine

Published: July 27, 2026Updated: August 27, 2026

Aminophylline/Ephedrine is a combination bronchodilator medication used primarily to treat respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It works through dual mechanisms: aminophylline relaxes smooth muscles in the airways, while ephedrine provides additional bronchodilation and decongestant effects by stimulating adrenergic receptors.

Quick summary

A dual-action bronchodilator combining aminophylline and ephedrine for treating asthma and COPD symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
690787
Generic
Aminophylline / Ephedrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Primarily used for asthma and COPD to relieve bronchospasm and breathing difficulties. May also be used for reversible airway obstruction and certain cases of respiratory distress.

Aminophylline (a theophylline derivative) relaxes bronchial smooth muscle by inhibiting phosphodiesterase and adenosine receptors. Ephedrine acts as a sympathomimetic agent, stimulating alpha and beta adrenergic receptors to produce bronchodilation and reduce nasal congestion.

This combination is less commonly used in modern practice due to the availability of safer alternatives. Both components have potential cardiovascular and CNS side effects. Requires careful monitoring and should only be used under healthcare provider supervision. Not recommended for patients with certain heart conditions, hypertension, or thyroid disorders.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy