Aminophylline / Ephedrine / Phenobarbital
Aminophylline/Ephedrine/Phenobarbital is an older combination respiratory medication containing two bronchodilators and a barbiturate sedative. This multi-ingredient formulation was historically used to treat asthma and chronic obstructive pulmonary disease (COPD) by relaxing airway muscles and reducing anxiety associated with breathing difficulties.
A historical combination respiratory medication for asthma and COPD containing two bronchodilators and a sedative component.
Key facts at a glance
- RxNorm
- 690789
- Generic
- Aminophylline / Ephedrine / Phenobarbital
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication was primarily used for the symptomatic treatment of asthma and COPD, particularly for relieving bronchospasm and associated breathing difficulties.
Aminophylline and ephedrine act as bronchodilators by relaxing smooth muscles in the airways, while phenobarbital provides sedative effects that may help reduce anxiety and improve breathing comfort.
This is an older medication combination that is largely considered outdated for modern practice. Individual component dosing varies, and this combination may cause drowsiness. It is typically not recommended for use in children, pregnant women, or patients with certain heart conditions. Modern asthma management typically relies on inhaled corticosteroids and newer long-acting bronchodilators.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy