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Aminophylline / Ephedrine / Phenobarbital / Potassium Iodide

Published: July 27, 2026Updated: August 27, 2026

This is a multi-ingredient respiratory medication combining four active components. The combination includes bronchodilators (aminophylline and ephedrine), a barbiturate sedative (phenobarbital), and an expectorant (potassium iodide). Historically used for respiratory conditions involving airway constriction and mucus production.

Quick summary

A combination respiratory medication containing bronchodilators, a sedative, and expectorant for managing asthma and COPD symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
690790
Generic
Aminophylline / Ephedrine / Phenobarbital / Potassium Iodide
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Historically prescribed for asthma, chronic obstructive pulmonary disease (COPD), and other conditions involving bronchoconstriction with excessive mucus production. Note: This is an older combination medication with limited use in modern practice.

Aminophylline and ephedrine relax bronchial smooth muscle to open airways; phenobarbital provides sedation to reduce anxiety and stabilize breathing; potassium iodide acts as an expectorant to help loosen and clear respiratory secretions.

Use requires careful monitoring due to potential drug interactions and side effects. The phenobarbital component carries risks of dependence, sedation, and respiratory depression. Patients should follow prescribing instructions closely and report any adverse effects to their healthcare provider. Not recommended for use during pregnancy.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy