Amlodipine / Benazepril
Amlodipine/Benazepril is a combination medication used to treat high blood pressure (hypertension). It combines two different classes of blood pressure medications—an ACE inhibitor and a calcium channel blocker—to help relax blood vessels and lower blood pressure more effectively than either medication alone. This combination is typically prescribed when single-agent therapy does not adequately control blood pressure.
A two-drug combination that lowers blood pressure by relaxing blood vessels through different mechanisms.
Key facts at a glance
- RxNorm
- 214223
- Generic
- Amlodipine / Benazepril
- Class
- multi-ingredient
- Brands
- Lotrel
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of hypertension (high blood pressure) in patients who require combination therapy to achieve adequate blood pressure control.
Benazepril is an ACE inhibitor that blocks the formation of angiotensin II, a substance that narrows blood vessels. Amlodipine is a calcium channel blocker that prevents calcium from entering smooth muscle cells in blood vessel walls, causing them to relax. Together, they lower blood pressure through complementary mechanisms.
May cause dizziness or lightheadedness, especially when starting treatment. Common side effects include cough, headache, and swelling. Should not be used during pregnancy. Patients should avoid potassium supplements and salt substitutes containing potassium unless directed, as ACE inhibitors can increase potassium levels. Alcohol may enhance blood pressure-lowering effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy