Amlodipine / Telmisartan
Amlodipine/Telmisartan is a combination antihypertensive medication that lowers blood pressure through two complementary mechanisms. It is used to treat essential hypertension in patients who require multi-drug therapy to achieve adequate blood pressure control. The combination allows for better efficacy than either component alone while potentially reducing side effects through lower individual doses.
A dual-action blood pressure medication combining a calcium channel blocker with an angiotensin receptor blocker for effective hypertension management.
Key facts at a glance
- RxNorm
- 901212
- Generic
- Amlodipine / Telmisartan
- Class
- multi-ingredient
- Brands
- Twynsta
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of essential hypertension in adults who are not adequately controlled on either amlodipine or telmisartan alone, or as initial therapy for patients requiring multi-drug treatment to reach blood pressure goals.
Amlodipine blocks L-type calcium channels in vascular smooth muscle, causing relaxation and vasodilation, while telmisartan blocks angiotensin II type 1 receptors, preventing vasoconstriction and reducing aldosterone secretion. Together they provide complementary blood pressure reduction with improved tolerability.
Avoid use during pregnancy (especially second and third trimesters) due to fetal harm risk. May cause hypotension, hyperkalemia, or renal impairment, particularly in patients with volume depletion or renal artery stenosis. Monitor for signs of angioedema. Avoid concomitant use with aliskiren in diabetic patients.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy