Amobarbital / Ephedrine
Amobarbital/Ephedrine is a combination medication containing a barbiturate sedative and a sympathomimetic bronchodilator. It was historically prescribed for respiratory conditions such as asthma and bronchitis, where the ephedrine component helped open airways while amobarbital provided calming effects. This medication has largely fallen out of favor due to the availability of safer alternatives.
A historical bronchodilator-sedative combination used for respiratory conditions like asthma.
Key facts at a glance
- RxNorm
- 691318
- Generic
- Amobarbital / Ephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for asthma and bronchial conditions to relieve bronchospasm and wheezing. May also have been used for allergic respiratory conditions and nasal congestion. Not commonly prescribed in modern practice due to safety concerns and availability of better-tolerated alternatives.
Ephedrine acts on alpha and beta adrenergic receptors to relax bronchial smooth muscle and reduce nasal congestion, while amobarbital provides central nervous system sedation and anxiolytic effects. The combination was designed to address both the physical and anxiety-related symptoms of respiratory conditions.
Contains a barbiturate with potential for dependence and abuse. Should be avoided in patients with cardiovascular disease, hypertension, hyperthyroidism, or glaucoma. Can cause drowsiness - avoid operating machinery. Due to safety concerns and the availability of safer alternatives like inhaled corticosteroids and beta-agonists, this medication is rarely used today.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy