Amoxicillin / Diclofenac
Amoxicillin/Diclofenac is a combination medication pairing an antibiotic with a nonsteroidal anti-inflammatory drug (NSAID). This combination is used when treatment requires addressing both bacterial infection and associated pain or inflammation simultaneously. The medication is typically reserved for specific clinical situations where both therapeutic effects are needed, such as certain post-procedural or infectious-inflammatory conditions.
A combination antibiotic and anti-inflammatory medication used for conditions requiring both infection treatment and pain/inflammation relief.
Key facts at a glance
- RxNorm
- 1008370
- Generic
- Amoxicillin / Diclofenac
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This combination medication is used for conditions involving both bacterial infection and significant pain or inflammation, such as certain dental procedures, orthopedic surgeries, or other infections where anti-inflammatory effects are clinically beneficial alongside antibiotic therapy.
Amoxicillin works by inhibiting bacterial cell wall synthesis, effective against susceptible gram-positive and some gram-negative bacteria. Diclofenac works by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause pain, fever, and inflammation.
As with all NSAIDs, diclofenac carries risks of gastrointestinal bleeding, cardiovascular events, and kidney impairment. Amoxicillin should not be used in penicillin-allergic patients. This combination requires careful evaluation of individual patient risk factors. Always complete the full antibiotic course as prescribed. Use only under direct medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy