Amoxicillin / Nystatin
Amoxicillin/Nystatin is a combination medication pairing an antibiotic with an antifungal agent. This combination is primarily used to prevent fungal infections, such as oral thrush, that can occur during prolonged antibiotic therapy. The antibiotic component treats bacterial infections while the antifungal component protects against opportunistic Candida overgrowth.
A combination antibiotic-antifungal used to prevent fungal infections during antibiotic treatment.
Key facts at a glance
- RxNorm
- 1008603
- Generic
- Amoxicillin / Nystatin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Prevention of fungal infections (particularly oral and esophageal candidiasis) during antibiotic therapy; may also be used for treating existing bacterial infections alongside prevention of secondary fungal infections
Amoxicillin interferes with bacterial cell wall synthesis to eliminate susceptible bacteria, while Nystatin binds to fungal cell membranes to eliminate Candida species by creating pores that cause cell contents to leak out
Not effective against viral infections; should be used with caution in patients with penicillin allergy; complete the full prescribed course; effectiveness may be reduced if taken with acidic foods or beverages; common side effects include gastrointestinal upset and oral discomfort with lozenges
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy