Amphotericin B / Triamcinolone
Amphotericin B/Triamcinolone is a topical combination medication that pairs an antifungal agent with a corticosteroid to treat inflammatory fungal skin infections. The antifungal component (Amphotericin B) works by binding to ergosterol in fungal cell membranes, while the corticosteroid (Triamcinolone) reduces associated inflammation, itching, and redness. This combination is particularly useful when treating conditions like tinea (ringworm) that present with significant inflammatory symptoms.
A topical antifungal-steroid combination for treating inflammatory fungal skin infections.
Key facts at a glance
- RxNorm
- 1007674
- Generic
- Amphotericin B / Triamcinolone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of dermatophyte and fungal infections of the skin accompanied by inflammation, including tinea corporis (ringworm), tinea cruris (jock itch), and similar conditions where both antifungal and anti-inflammatory effects are desired.
Amphotericin B binds to ergosterol in fungal cell membranes, creating pores that disrupt cell integrity and lead to fungal cell death. Triamcinolone is a glucocorticoid that suppresses inflammatory responses by inhibiting phospholipase A2 and reducing cytokine production, thereby alleviating redness, swelling, and itching.
For topical dermatological use only—avoid contact with eyes and mucous membranes. Do not apply to open wounds or broken skin. Treatment duration should follow prescribing guidance to minimize steroid-related side effects such as skin thinning. Systemic absorption is minimal with proper use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy