Ampicillin / Dicloxacillin
Ampicillin/Dicloxacillin is a combination of two penicillin-type antibiotics that provides broad-spectrum coverage against various bacterial infections. This combination works synergistically to inhibit bacterial cell wall synthesis, making it effective against both penicillin-susceptible organisms and penicillinase-producing bacteria.
A broad-spectrum combination antibiotic used to treat various bacterial infections by inhibiting cell wall synthesis.
Key facts at a glance
- RxNorm
- 1008820
- Generic
- Ampicillin / Dicloxacillin
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats respiratory tract infections, skin and soft tissue infections, urinary tract infections, and other bacterial infections caused by susceptible organisms. Often used when infection sources are unknown or mixed flora are suspected.
Both antibiotics bind to penicillin-binding proteins (PBPs) in the bacterial cell wall, inhibiting transpeptidation and preventing cross-linking of peptidoglycan chains. This weakens the cell wall and leads to bacterial cell death. Dicloxacillin specifically resists degradation by penicillinase enzymes produced by certain bacteria.
Should not be used in patients with penicillin allergy. Common side effects include gastrointestinal symptoms (nausea, diarrhea), rash, and allergic reactions. Full course must be completed as prescribed. Effectiveness may be reduced by tetracyclines and macrolides if taken concurrently.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy