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Amylase / Papain / Protease

Published: July 27, 2026Updated: August 27, 2026

This is a multi-ingredient digestive enzyme supplement containing amylase, papain, and protease. It is used to aid the digestion of carbohydrates, proteins, and fats by supplementing the body's natural digestive enzymes. It is typically prescribed or recommended for patients with pancreatic insufficiency, digestive disorders, or those experiencing general digestive discomfort after meals.

Quick summary

A digestive enzyme supplement combining amylase, papain, and protease to help break down carbohydrates and proteins in the digestive tract.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1372677
Generic
Amylase / Papain / Protease
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

This medication is used to treat digestive enzyme deficiencies, pancreatic insufficiency, and general digestive problems including bloating, gas, and indigestion after meals. It may also be used in conditions such as chronic pancreatitis, cystic fibrosis-related pancreatic insufficiency, or post-surgical digestive issues.

The three enzymes work together to break down food components: amylase breaks down carbohydrates and starches into sugars, papain (a plant-based protease) and protease break down proteins into amino acids, facilitating nutrient absorption in the intestines.

Should be taken with meals and swallowed whole without crushing or chewing. Patients with pork allergies should exercise caution as some enzyme products are pork-derived. Side effects may include nausea, abdominal cramps, or diarrhea. Always consult a healthcare provider before use, especially if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy