Anidulafungin
Anidulafungin is an echinocandin-class antifungal medication used to treat serious fungal infections, particularly invasive candidiasis and aspergillosis. It works by inhibiting fungal cell wall synthesis, making it effective against fungi that are resistant to other antifungal agents.
Anidulafungin is an injectable antifungal medication used for serious systemic fungal infections when other treatments are not appropriate.
Key facts at a glance
- ATC
- J02AX06
- RxNorm
- 341018
- Generic
- Anidulafungin
- Class
- atc-j02
- Brands
- Eraxis
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 200mg loading dose then 100mg once daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 3mg/kg loading dose then 1.5mg/kg once daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 200mg loading dose then 100mg once daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
9 groupspregnancy
first trimesteravoid if possible
Avoid use during pregnancy unless benefits outweigh risks. Use only if potential benefits justify potential risks to the fetus.
regular fetal monitoring, ultrasound assessments
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse with caution
Use only if clearly needed. Consider benefits versus risks of treating candidiasis.
regular prenatal check-ups, fetal growth monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse with caution
Use only if benefits outweigh risks. Not recommended for prophylactic use.
fetal monitoring, assessment of labor
Use with caution and monitor for adverse effects.
lactation
breastfeedingdiscontinue breastfeeding or avoid drug
Breastfeeding is not recommended during treatment with anidulafungin due to unknown excretion in breast milk
monitor infant for adverse effects
pediatric_age
neonates and infantsweight-based dosing required
Approved for use in pediatric patients including neonates. Dose: loading dose 3 mg/kg IV, maintenance 1.5 mg/kg daily
monitor liver function tests, assess clinical response
geriatric
elderlyno adjustment needed
No specific dose adjustment required for elderly patients. Use standard adult dosing.
monitor renal and hepatic function, assess for drug interactions
renal_impairment
severe renal impairmentno adjustment needed
No dose adjustment required for any degree of renal impairment, including patients on hemodialysis
standard monitoring
hepatic_impairment
mild to moderateno adjustment needed
No dose adjustment required for mild to moderate hepatic impairment
monitor liver function tests periodically
hepatic_impairment
severeconsider_reduction
Use with caution in severe hepatic impairment. Consider reducing maintenance dose. Clinical data limited.
frequent liver function monitoring, assess clinical response
Use with caution and monitor for adverse effects.
Statistics and clinical data
Drug class
Antifungal class classification
Common uses
Therapeutic indications
Mechanism of action
Pharmacological mechanism
FDA approval year
Regulatory approval timeline
Treatment of invasive candidiasis (including candidemia) in adult patients with neutropenia or other immunocompromised states, and for the treatment of esophageal candidiasis when other antifungal therapies are not appropriate.
Anidulafungin is an echinocandin that inhibits beta-(1,3)-D-glucan synthase, an enzyme essential for fungal cell wall synthesis, leading to cell death of susceptible fungi.
Administered by intravenous infusion only. Generally well-tolerated but may cause liver enzyme elevations. Limited data in pregnancy and breastfeeding. Requires reconstitution and specific infusion instructions.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy