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Antipyrine / Caffeine

Published: July 27, 2026Updated: August 27, 2026

Antipyrine/Caffeine is a combination otic medication used to relieve pain and inflammation associated with ear infections, particularly acute otitis media. The antipyrine component provides analgesic and anti-inflammatory effects, while caffeine may enhance absorption and contribute to pain relief.

Quick summary

An otic analgesic combination medication used to relieve ear pain and inflammation from infections.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1007237
Generic
Antipyrine / Caffeine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Symptomatic relief of pain and inflammation in acute otitis media and other ear conditions requiring analgesia

Antipyrine provides analgesic and antipyretic effects; caffeine may enhance analgesic efficacy and improve absorption of the primary active ingredient

For otic use only; avoid contaminating the dropper tip; use with caution if eardrum perforation is suspected; not for prolonged use without medical supervision

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy