Antipyrine / Ephedrine
Antipyrine/Ephedrine is a combination medication containing an analgesic-antipyretic agent and a sympathomimetic decongestant. This combination has been used to provide relief from respiratory symptoms associated with colds, allergies, and sinusitis by addressing both pain/fever and nasal congestion. The medication works through complementary mechanisms of its two active ingredients.
A combination analgesic and decongestant used for symptomatic relief of respiratory conditions.
Key facts at a glance
- RxNorm
- 1007156
- Generic
- Antipyrine / Ephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of nasal congestion, sinus pressure, headache, and fever associated with upper respiratory infections such as colds, influenza, and allergic rhinitis.
Antipyrine provides analgesic and antipyretic effects, while ephedrine acts as a sympathomimetic agent that stimulates alpha-adrenergic receptors in nasal blood vessels, causing vasoconstriction and reducing swelling/congestion.
Use with caution in patients with cardiovascular disease, hypertension, thyroid disorders, diabetes, or glaucoma due to ephedrine's stimulant effects. Avoid in patients taking MAO inhibitors. Not recommended during pregnancy without medical supervision. May cause insomnia, nervousness, or elevated blood pressure in some individuals.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy