Antipyrine / Phenylephrine
Antipyrine/Phenylephrine is a combination ear drop medication used to relieve ear congestion, pressure, and discomfort. Antipyrine provides analgesic and anti-inflammatory effects while phenylephrine acts as a decongestant to reduce swelling in the ear canal. This medication is commonly prescribed for ear fullness and temporary relief of ear symptoms associated with congestion.
A combination ear drop that relieves ear congestion, pressure, and discomfort through analgesic and decongestant actions.
Key facts at a glance
- RxNorm
- 689242
- Generic
- Antipyrine / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of ear congestion, fullness, pressure, and discomfort in the ear canal; commonly used for temporary relief of ear symptoms associated with congestion from colds, allergies, or eustachian tube dysfunction; may be used in management of acute otitis media symptoms.
Antipyrine is an analgesic and antipyretic agent that helps reduce pain and inflammation in the ear. Phenylephrine is a topical decongestant that constricts blood vessels in the ear canal, reducing swelling and congestion. Together they address both the pain and the underlying congestion causing ear discomfort.
For topical ear use only; avoid contact with eyes; not recommended for use in patients with certain ear conditions such as perforated eardrums unless specifically directed by a physician; efficacy may be reduced if the ear canal is blocked with excessive earwax; consult a healthcare provider if symptoms persist or worsen.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy