Amikacin
Arikayce is an inhaled antibiotic suspension used to treat Mycobacterium avium complex (MAC) lung disease in adults who have not achieved adequate response to standard antibiotic treatment. The medication delivers amikacin directly to the lungs via nebulization, helping to reduce bacterial load and improve respiratory symptoms in this chronic infection.
Arikayce is an inhaled antibiotic for treating resistant MAC lung infections in adults who haven't responded to conventional therapy.
Key facts at a glance
- RxNorm
- 2059185
- Generic
- Arikayce
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Arikayce is indicated for the treatment of Mycobacterium avium complex (MAC) lung disease in adults who have not achieved negative sputum cultures after at least 6 months of a guideline-based multidrug regimen (partial treatment regimen). It is used as part of a combination therapy with other antibiotics.
Arikayce contains amikacin, an aminoglycoside antibiotic, encapsulated in liposomes that are inhaled directly into the lungs. The liposomal formulation allows for sustained release and improved delivery to the site of infection. Amikacin works by inhibiting bacterial protein synthesis, effectively killing the MAC bacteria.
Common side effects include cough, dyspnea, bronchospasm, and dysphonia. Arikayce carries a Boxed Warning for increased risk of respiratory adverse reactions and ototoxicity (hearing loss). It should be used with caution in patients with renal impairment and requires regular monitoring. The medication is administered once daily via a specialized nebulizer device.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 2, 2026. · Read our editorial policy