Nelarabine
Arranon is a chemotherapy medication used to treat certain types of T-cell cancers, specifically T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. It is typically prescribed when the cancer has not responded to other treatments or has returned after initial therapy. This medication is administered intravenously by healthcare professionals in a clinical setting.
Arranon is an anticancer medication used to treat T-cell leukemias and lymphomas that have relapsed or not responded to other treatments.
Key facts at a glance
- RxNorm
- 613324
- Generic
- Arranon
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) in adult and pediatric patients who have not responded to or have relapsed after at least two prior treatment regimens.
Arranon is an antimetabolite prodrug that is converted to arabinofuranosylguanine (ara-G), which gets incorporated into DNA. This incorporation leads to inhibition of DNA synthesis and triggers apoptosis (programmed cell death) in malignant T-cells.
This medication carries a risk of serious neurological toxicities, including neuropathy, seizures, and coma. Patients require close monitoring during and after treatment. It is administered by intravenous infusion, typically in a hospital or clinical setting. Common side effects include fatigue, nausea, and low blood cell counts. Use should be supervised by oncologists experienced with chemotherapy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 2, 2026. · Read our editorial policy