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Ascorbic Acid

Published: July 26, 2026Updated: August 24, 2026

Ascorbic acid, or vitamin C, is an essential nutrient crucial for collagen synthesis, immune function, and antioxidant protection in the body.

Quick summary

Ascorbic acid is an essential vitamin supplement used to prevent and treat vitamin C deficiency while supporting immune function and collagen production.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

ATC
A11GA01
RxNorm
1151
Generic
Ascorbic Acid
Class
atc-a11
Brands
Ferocon, Ferraplus, Folivane-F, Hemax, Icar-C Plus, Icar C, Macuvite with Lutein, Multi-Delyn, Irospan Tablet, Lactocal, Vitafol-One, Halls Defense, Infuvite, Infuvite Pediatric, Concept OB
Availability
rx
Lactation
unknown
Routes
oral, topical
Forms
tablet, capsule, solution, suspension, cream, powder
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose exceeding 10 grams may cause significant gastrointestinal distress and metabolic disturbances
Chronic overdose: Prolonged intake exceeding 2000mg daily may lead to oxalate kidney stone formation, iron overload in susceptible individuals, and rebound scurvy upon discontinuation
Immediate actions
Discontinue supplement, maintain hydration, monitor renal function, provide symptomatic treatment for gastrointestinal effects
Antidote
No specific antidote available(Supportive care is primary treatment; no targeted antidote exists)
Poison Control: 1-800-222-1222

Special Populations

11 groups
✓

pregnancy

first trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed for normal dietary intake

Key Recommendations

continue normal dietary intake; supplementation only if deficient

Monitor

prenatal checkups

✓

pregnancy

second trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed for normal dietary intake

Key Recommendations

maintain adequate intake through diet or prenatal vitamins

Monitor

routine prenatal monitoring

✓

pregnancy

third trimester
safe
FDA Category
C
Dose Adjustment

no adjustment needed for normal dietary intake

Key Recommendations

continue standard prenatal vitamin supplementation

Monitor

routine prenatal monitoring

✓

lactation

general
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

continue normal dietary intake; safe for breastfeeding mothers

Monitor

none required

✓

pediatric_age

infants
safe
FDA Category
C
Dose Adjustment

age-appropriate dosing required

Key Recommendations

use pediatric formulations; do not exceed recommended daily allowance

Monitor

monitor for adverse GI effects

✓

pediatric_age

children
safe
FDA Category
C
Dose Adjustment

age-appropriate dosing required

Key Recommendations

follow age-specific dosage guidelines; prefer dietary sources

Monitor

monitor for adverse GI effects

✓

geriatric

general
safe
FDA Category
C
Dose Adjustment

no adjustment needed for normal renal function

Key Recommendations

continue regular intake; may benefit from supplementation if diet deficient

Monitor

monitor renal function periodically

⚠

renal_impairment

mild
caution
FDA Category
C
Dose Adjustment

use caution with high doses

Key Recommendations

avoid high doses; maintain normal dietary intake

Monitor

monitor renal function and urine oxalate levels

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe
caution
FDA Category
C
Dose Adjustment

avoid high doses

Key Recommendations

limit to dietary intake only; avoid supplementation

Monitor

close monitoring of renal function and oxalate levels

Use with caution and monitor for adverse effects.

✓

hepatic_impairment

mild to moderate
safe
FDA Category
C
Dose Adjustment

no adjustment needed

Key Recommendations

continue normal dietary intake

Monitor

none specifically required

✓

alcohol_users

general
safe
FDA Category
C
Dose Adjustment

may benefit from slightly higher intake

Key Recommendations

may consider supplementation due to increased excretion; maintain balanced diet

Monitor

none specifically required

Statistics and clinical data

drug_classWHO
2023

Drug class

Value:Vitamin

ATC code: A11GA01 (Ascorbic Acid)

usageNIH
2023

Common uses

Value:Vitamin C supplementation, scurvy treatment, antioxidant

Primary therapeutic applications

safetyFDA
2023

Safety profile

Value:Generally Recognized as Safe (GRAS)

FDA safety classification

availabilityFDA
2023

Availability

Value:Over-the-counter

Prescription status

Treatment and prevention of vitamin C deficiency (scurvy), nutritional supplementation when dietary intake is insufficient, support of wound healing processes, and as an antioxidant supplement in cases of increased oxidative stress.

Ascorbic acid serves as a reducing agent in numerous biochemical reactions. It is essential for the synthesis of collagen, carnitine, and catecholamines. It also enhances non-heme iron absorption in the gut and supports various immune cell functions.

Generally well-tolerated when taken at recommended amounts. High doses may cause gastrointestinal disturbances. Should be used with caution in patients with a history of kidney stones or renal impairment. Natural sources include citrus fruits, berries, and leafy green vegetables.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy