Calaspargase Pegol
Asparlas is a chemotherapy medication used to treat acute lymphoblastic leukemia (ALL) in pediatric and young adult patients. It contains an enzyme called L-asparaginase, which works by depleting asparagine—an amino acid that cancer cells need to grow and multiply. This medication is administered as an intravenous infusion and is typically used as part of a multi-drug chemotherapy regimen.
Asparlas is an L-asparaginase chemotherapy agent used to treat acute lymphoblastic leukemia in pediatric and young adult patients.
Key facts at a glance
- RxNorm
- 2121422
- Generic
- Asparlas
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Asparlas is indicated for the treatment of acute lymphoblastic leukemia (ALL) in patients aged 1 month to 21 years old. It is used as a component of multi-agent chemotherapy regimens.
Asparlas contains L-asparaginase, an enzyme that hydrolyzes the amino acid asparagine into aspartic acid and ammonia. By depleting circulating asparagine, the drug deprives leukemic cells of this essential nutrient they cannot synthesize themselves, leading to cell death.
Asparlas is administered intravenously every 3 weeks. Common side effects include elevated liver enzymes, pancreatitis, allergic reactions, and blood clotting abnormalities. Patients require regular monitoring of liver function, pancreatic enzymes, and coagulation parameters during treatment. It should not be used in patients with serious hypersensitivity to asparaginase products.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 2, 2026. · Read our editorial policy