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Aspirin / Caffeine

Published: July 27, 2026Updated: August 27, 2026

Aspirin/Caffeine is a combination medication used for the relief of headache, migraine, toothache, menstrual cramps, and minor aches and pains. The aspirin component provides analgesic and anti-inflammatory effects, while caffeine acts as a mild stimulant that may enhance pain relief and help constrict blood vessels associated with headaches. This combination is typically used by adults seeking faster or more effective relief for tension headaches and mild to moderate pain.

Quick summary

A combination analgesic and stimulant used to treat headaches and mild to moderate pain by combining aspirin's pain-relieving properties with caffeine's enhancing effects.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
214250
Generic
Aspirin / Caffeine
Class
multi-ingredient
Brands
Stanback Headache Powder Reformulated Jan 2011, BC Arthritis, BC Original Formula, Anacin
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Relief of tension headaches, migraine headaches, menstrual cramps, toothache, muscle pain, and fever. May also be used for general pain relief when combined aspirin-caffeine formulations are preferred.

Aspirin inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause pain and inflammation. Caffeine is a methylxanthine stimulant that may enhance the absorption of analgesics, increase alertness, and help constrict dilated blood vessels in the brain that contribute to headache pain.

Not recommended for children or teenagers due to risk of Reye's syndrome. Should be avoided by those with aspirin allergy, bleeding disorders, or stomach ulcers. Caffeine content may cause insomnia, nervousness, or rapid heartbeat in sensitive individuals. Avoid alcohol and consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy