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Aspirin / Caffeine / Ipecac / Opium

Published: July 27, 2026Updated: August 27, 2026

This multi-ingredient medication combines aspirin, caffeine, ipecac, and opium. It appears to be an older analgesic formulation that leverages the pain-relieving properties of aspirin and opium, with caffeine potentially enhancing analgesic effects. The inclusion of ipecac suggests it may have been used for specific gastrointestinal or pain-related conditions.

Quick summary

A multi-ingredient analgesic combining aspirin, caffeine, ipecac, and opium for pain management.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
689516
Generic
Aspirin / Caffeine / Ipecac / Opium
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Historically used for moderate to severe pain relief, particularly when associated with gastrointestinal symptoms. The opium component may provide anti-diarrheal effects, while aspirin addresses inflammation and pain.

Aspirin provides analgesic and anti-inflammatory effects through COX enzyme inhibition. Caffeine may enhance aspirin absorption and pain relief. Opium acts on opioid receptors to reduce pain perception and slow GI motility. Ipecac induces vomiting, though its purpose in this combination is unclear.

Many of the individual components in this formulation are no longer commonly used or recommended in modern medicine. Ipecac is generally discouraged for poisoning treatment. Opium carries risk of dependence. Patients should consult healthcare providers about current alternative treatments with better safety profiles.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy