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Aspirin / Carisoprodol / Codeine

Published: July 27, 2026Updated: August 27, 2026

This combination medication contains aspirin (a pain reliever and anti-inflammatory), carisoprodol (a muscle relaxant), and codeine (an opioid analgesic). It is prescribed for short-term treatment of acute, severe musculoskeletal pain and spasms when other treatments have not been effective. The three ingredients work together to address both pain and the associated muscle tension.

Quick summary

A short-term combination pain treatment containing an NSAID, muscle relaxant, and opioid for severe musculoskeletal pain.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
689522
Generic
Aspirin / Carisoprodol / Codeine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Acute musculoskeletal pain and spasms, typically when other analgesics or muscle relaxants alone have proven insufficient. Usually reserved for short-term use due to the opioid component.

Aspirin inhibits cyclooxygenase enzymes to reduce pain and inflammation; carisoprodol acts on the central nervous system to relax skeletal muscles; codeine binds to opioid receptors to reduce pain perception. The combination addresses multiple pathways of pain and muscle spasm.

Contains an opioid (codeine) with risk of dependence, sedation, and respiratory depression. Carisoprodol may cause drowsiness and has potential for abuse. Aspirin carries risk of GI bleeding and is contraindicated in certain patients. This combination is generally not recommended for long-term use and is subject to stricter prescribing regulations. Patients should avoid alcohol and operate machinery until they know how the medication affects them.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy