Aspirin / Chlorpheniramine
Aspirin/Chlorpheniramine is a combination medication that pairs a pain reliever and fever reducer with an antihistamine. This combination is typically used to treat symptoms of colds, flu, or allergies that include aches, fever, sneezing, and runny nose.
A cold and allergy symptom reliever combining aspirin for pain/fever with chlorpheniramine for allergic reactions.
Key facts at a glance
- RxNorm
- 816818
- Generic
- Aspirin / Chlorpheniramine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves common cold and flu symptoms such as headache, fever, body aches, sneezing, runny nose, and itchy/watery eyes associated with respiratory illnesses or allergic reactions.
Aspirin works by inhibiting cyclooxygenase (COX) enzymes to reduce prostaglandin production, thereby decreasing pain, inflammation, and fever. Chlorpheniramine is an antihistamine that blocks H1 histamine receptors, reducing allergic symptoms like sneezing, itching, and nasal discharge.
Should not be used in children or teenagers recovering from viral infections due to Reye's syndrome risk. May cause drowsiness; avoid alcohol and operating machinery. Contraindicated in people with aspirin allergy, bleeding disorders, or those taking blood thinners. Consult a doctor before use if pregnant, nursing, or taking other medications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy