Aspirin / Chlorpheniramine / Phenylpropanolamine
This multi-ingredient medication combines an analgesic (aspirin), an antihistamine (chlorpheniramine), and a decongestant (phenylpropanolamine) to address multiple cold and allergy symptoms simultaneously. It is typically used for temporary relief of nasal congestion, headache, body aches, sneezing, and runny nose associated with upper respiratory conditions.
A cold and allergy symptom relief medication combining pain/fever reduction, antihistamine, and decongestant properties.
Key facts at a glance
- RxNorm
- 816174
- Generic
- Aspirin / Chlorpheniramine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of common cold symptoms including nasal congestion, sinus pressure, headache, minor aches and pains, runny nose, and sneezing. May also be used for allergic rhinitis symptoms.
Aspirin provides analgesic and anti-inflammatory effects for pain and fever. Chlorpheniramine blocks histamine receptors to reduce allergic symptoms like sneezing and runny nose. Phenylpropanolamine constricts blood vessels in nasal passages to decrease congestion.
Should not be used in children recovering from viral infections due to Reye's syndrome risk associated with aspirin. May cause drowsiness; avoid operating machinery. Consult a doctor if you have hypertension, heart disease, thyroid disorders, or are taking blood thinners. Do not combine with other products containing NSAIDs or antihistamines.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy