Aspirin / Glycine
Aspirin/Glycine is a combination medication that pairs the analgesic and anti-inflammatory properties of aspirin with glycine, an amino acid that may help improve tolerability. This formulation is designed for individuals who require aspirin therapy but may benefit from enhanced gastrointestinal comfort compared to standard aspirin products.
A buffered aspirin formulation combining pain-relieving aspirin with glycine for potentially improved stomach tolerance.
Key facts at a glance
- RxNorm
- 392499
- Generic
- Aspirin / Glycine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Relief of mild to moderate pain, fever, and inflammation; may also be used for antiplatelet effects in cardiovascular applications. The glycine component aims to reduce potential stomach irritation associated with aspirin therapy.
Aspirin inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis to provide analgesic, anti-inflammatory, and antiplatelet effects. Glycine acts as a buffering agent and may help protect the gastric lining, potentially reducing irritation and improving overall tolerability of the aspirin component.
May cause gastrointestinal discomfort, bleeding risk, or allergic reactions in susceptible individuals. Avoid use in patients with aspirin allergy, bleeding disorders, or those taking blood thinners unless specifically directed by a healthcare provider. Not recommended for children with viral infections due to Reye's syndrome risk. Consult a doctor before use if pregnant, nursing, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy