Aspirin / Isosorbide
Aspirin/Isosorbide is a combination medication used primarily for cardiovascular conditions, particularly for the treatment and prevention of angina (chest pain). Aspirin provides antiplatelet effects to help prevent blood clots, while isosorbide (a nitrate) helps dilate blood vessels to improve blood flow and reduce the heart's workload. This combination is typically prescribed for patients with coronary artery disease or those who have experienced certain cardiovascular events.
A cardiovascular medication combining aspirin and isosorbide to prevent angina and reduce the risk of heart-related events through antiplatelet and vasodilatory effects.
Key facts at a glance
- RxNorm
- 1007337
- Generic
- Aspirin / Isosorbide
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication is primarily used to treat and prevent angina (chest pain) caused by coronary artery disease. It may also be prescribed for secondary prevention of heart attacks and strokes in appropriate patients.
Aspirin inhibits platelet aggregation by blocking thromboxane A2 synthesis, reducing the formation of blood clots. Isosorbide, a nitrate, releases nitric oxide which causes vasodilation of veins and arteries, decreasing cardiac workload and improving oxygen supply to the heart muscle.
This medication should not be used in patients with certain bleeding disorders, severe anemia, or those taking other anticoagulants without medical supervision. Common side effects may include headache, dizziness, or gastrointestinal discomfort. Patients should not discontinue this medication abruptly without consulting their healthcare provider.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy