Aspirin / Methocarbamol
Aspirin/Methocarbamol is a combination medication pairing a nonsteroidal anti-inflammatory drug (NSAID) with a muscle relaxant. This combination is primarily used to treat acute, painful musculoskeletal conditions such as muscle spasms, strains, and sprains, where both anti-inflammatory/analgesic effects and muscle relaxation are needed.
Combination medication used for acute musculoskeletal pain and muscle spasms.
Key facts at a glance
- RxNorm
- 214255
- Generic
- Aspirin / Methocarbamol
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of acute, painful musculoskeletal conditions including muscle spasms, strains, sprains, and associated discomfort where both pain/inflammation relief and muscle relaxation are desired.
Methocarbamol acts on the central nervous system to produce muscle relaxant effects, while aspirin provides analgesic and anti-inflammatory effects through inhibition of cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.
May cause drowsiness or dizziness; avoid alcohol and operating machinery until effects are known. Aspirin component carries risk of gastrointestinal bleeding and should be avoided before surgery. Not recommended during pregnancy, in patients with bleeding disorders, or with concurrent NSAID use. Consult healthcare provider regarding all current medications to avoid interactions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy