Aspirin / Papaverine / Phenobarbital
Aspirin/Papaverine/Phenobarbital is a combination medication that combines an antiplatelet agent, a smooth muscle relaxant, and a barbiturate sedative. This multi-ingredient formulation has been used historically for vascular conditions involving abnormal smooth muscle contraction and platelet aggregation. The combination works synergistically to promote vasodilation, reduce platelet clumping, and provide calming effects.
A combination medication with antiplatelet, vasodilating, and sedative properties used for certain vascular conditions.
Key facts at a glance
- RxNorm
- 1009038
- Generic
- Aspirin / Papaverine / Phenobarbital
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Historically used for peripheral vascular disorders, vascular headaches, and conditions involving abnormal vasoconstriction and platelet aggregation. Less commonly used in modern practice due to the availability of more targeted therapies.
Aspirin inhibits platelet aggregation and provides anti-inflammatory effects; papaverine acts as a smooth muscle relaxant causing vasodilation; phenobarbital produces sedative and anxiolytic effects through CNS depression. Together, they address both vascular tone and platelet function.
Use of barbiturates like phenobarbital carries risks of dependence, tolerance, and CNS depression. Aspirin component may cause GI irritation and bleeding risk. This is an older combination with limited use in contemporary medicine; individual components are more commonly prescribed separately for better dose control. Avoid in pregnancy, respiratory depression, and with other CNS depressants.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy