Aspirin / Promethazine / Pseudoephedrine
This multi-ingredient medication combines aspirin, promethazine, and pseudoephedrine to address multiple cold and flu symptoms simultaneously. It provides relief from pain, fever, nasal congestion, and may help with nausea or allergic symptoms associated with respiratory infections.
A combination cold and flu remedy addressing pain, fever, congestion, and nausea through three complementary active ingredients.
Key facts at a glance
- RxNorm
- 689540
- Generic
- Aspirin / Promethazine / Pseudoephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of symptoms associated with the common cold, flu, or upper respiratory allergies, including headache, fever, body aches, nasal congestion, sinus pressure, runny nose, sneezing, and nausea
Aspirin provides analgesic and antipyretic effects by inhibiting prostaglandin synthesis; promethazine blocks histamine receptors and has antiemetic properties; pseudoephedrine acts as a decongestant by causing vasoconstriction of nasal blood vessels, reducing swelling and congestion
Not recommended for children under 12 due to aspirin-related Reye's syndrome risk; should be avoided in patients taking blood thinners or with stomach ulcers; may cause drowsiness; pseudoephedrine is subject to purchase restrictions in many regions due to its potential for misuse; consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy