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Aspirin / Pseudoephedrine

Published: July 27, 2026Updated: August 27, 2026

Aspirin/Pseudoephedrine is a combination medication used to temporarily relieve multiple symptoms of colds, allergies, or flu, including nasal congestion, sinus pressure, headache, minor aches and pains, and fever. The aspirin component provides pain relief and fever reduction, while pseudoephedrine works as a decongestant to reduce nasal swelling and congestion.

Quick summary

A combination cold and allergy medication that relieves congestion, pain, and fever by combining a pain reliever with a decongestant.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
214259
Generic
Aspirin / Pseudoephedrine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves nasal and sinus congestion, headache, minor body aches and pains, and fever associated with the common cold, allergies, or other upper respiratory conditions.

Aspirin works by reducing hormones that cause inflammation and pain in the body, while pseudoephedrine constricts blood vessels in the nasal passages, reducing swelling and congestion to make breathing easier.

Not recommended for children under 12 due to Reye's syndrome risk. Should be avoided by those with certain heart conditions, high blood pressure, thyroid disorders, or who are taking MAO inhibitors. Consult a healthcare provider before use if pregnant, nursing, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy