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Atazanavir Sulfate

Published: July 26, 2026Updated: August 27, 2026

Atazanavir Sulfate is an antiretroviral medication classified as a protease inhibitor, used in combination with other HIV medications to manage human immunodeficiency virus (HIV) infection. It helps reduce the amount of HIV in the body, allowing the immune system to function more effectively and reducing the risk of HIV-related complications.

Quick summary

Atazanavir Sulfate is an HIV protease inhibitor used as part of combination therapy to suppress HIV viral load.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
358299
Generic
Atazanavir Sulfate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Atazanavir Sulfate is indicated for the treatment of HIV-1 infection in adults and pediatric patients. It is used as part of combination antiretroviral therapy (ART) and is not a cure for HIV but helps control viral replication.

As a protease inhibitor, Atazanavir works by inhibiting the HIV protease enzyme, which is essential for the assembly and maturation of infectious HIV particles. By blocking this enzyme, the medication prevents the virus from replicating effectively.

Atazanavir should be taken with food for optimal absorption. Common side effects include jaundice (yellowing of skin/eyes) due to increased bilirubin levels, nausea, and headache. Patients should be monitored for kidney stones and liver function. Drug interactions are common with many medications including certain statins, acid reducers, and antipsychotics. Resistance may develop if used inconsistently.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy