Atenolol / Chlorthalidone
Atenolol/Chlorthalidone is a combination medication used to treat high blood pressure (hypertension). It contains two active ingredients: atenolol, a beta-blocker that reduces heart rate and workload on the heart, and chlorthalidone, a diuretic that helps the body eliminate excess fluid and salt. This combination is typically prescribed when single-agent therapy is insufficient for blood pressure control.
A combination blood pressure medication pairing a beta-blocker with a diuretic for enhanced hypertension management.
Key facts at a glance
- RxNorm
- 151195
- Generic
- Atenolol / Chlorthalidone
- Class
- multi-ingredient
- Brands
- Tenoretic
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to treat essential hypertension (high blood pressure) in patients who require combination therapy for adequate blood pressure control.
Atenolol blocks beta-1 adrenergic receptors in the heart, reducing heart rate and cardiac output, while chlorthalidone inhibits sodium reabsorption in the kidney's distal tubule, promoting water and salt excretion to decrease fluid volume.
May cause dizziness or fatigue; avoid alcohol; do not stop taking abruptly without medical guidance; monitor for electrolyte imbalances (especially potassium) and blood pressure regularly; inform your doctor of all medications being taken to avoid interactions.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy