Efavirenz Emtricitabine Tenofovir
Atripla is a combination antiretroviral medication used to treat HIV-1 infection in adults and children. It combines three drugs that work together to suppress the virus and improve immune function. This medication is typically prescribed for patients who have not been treated with antiretroviral therapy before or meet specific clinical criteria.
Atripla is a three-drug combination pill used as a complete HIV treatment regimen.
Key facts at a glance
- RxNorm
- 643067
- Generic
- Atripla
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Atripla is indicated for the treatment of HIV-1 infection in adults and children weighing at least 40 kg (88 lbs) who meet specific treatment criteria. It is used as a complete antiretroviral regimen and is typically prescribed for treatment-naive patients or those without documented resistance to its components.
Atripla combines efavirenz (an NNRTI) with emtricitabine and tenofovir disoproxil fumarate (both NRTIs). These drugs inhibit reverse transcriptase, an enzyme HIV needs to replicate, thereby suppressing viral replication and reducing HIV viral load while allowing immune recovery.
Atripla is not a cure for HIV and must be taken consistently to remain effective. Common side effects include vivid dreams, dizziness, headache, and rash; CNS effects may occur especially during the first few weeks. It should be taken on an empty stomach at bedtime, and patients should be monitored for kidney function and bone density. Resistance testing is recommended before initiating treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 2, 2026. · Read our editorial policy